Prolonged Role of Itraconazole in the Treatment of Allergic Bronchopulmonary Aspergillosis
نویسندگان
چکیده
Oral corticosteroids are first-line therapy for allergic bronchopulmonary aspergillosis (ABPA), however, itraconazole has been recognized as an adjunctive treatment. This paper describes the prolonged use of itraconazole in an asthmatic patient with a diagnosis of ABPA. This case report features a patient who showed benefit with a longer duration of itraconazole therapy without demonstrating adverse events related to treatment over nearly eight years. Prolonged treatment with itraconazole may serve as a corticosteroid sparing option for ABPA patients.
منابع مشابه
[Prolonged therapeutic response to voriconazole in a case of allergic bronchopulmonary aspergillosis].
Allergic bronchopulmonary aspergillosis is a lung disease characterized by an immune response to several antigens of Aspergillus species. Corticosteroids are the treatment of choice in the acute phase, although some studies have shown the efficacy of itraconazole. We describe the case of a favorable, prolonged therapeutic response to voriconazole in a patient with allergic bronchopulmonary aspe...
متن کاملElevated levels of exhaled nitric oxide in recurrent tonsillitis.
REFERENCES 1 Stevens DA, Moss RB, Kurup VP, et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis – state of the art: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 2003; 37: Suppl. 3, S225–S264. 2 Skowronski E, Fitzgerald DA. Life-threatening allergic bronchopulmonary aspergillosis in a well child with cystic fibrosis. Med J Aust 2005; 182: 482–483. 3 Skov M, Main...
متن کاملProficiency testing of first- and second-line anti-tuberculosis drugs in Italy.
bronchopulmonary aspergillosis. Ann Allergy Asthma Immunol 1999; 82: 511–516. 4 Salez F, Brichet A, Desurmont S, et al. Effect of itraconazole therapy in allergic bronchopulmonary aspergillosis. Chest 1999; 116: 1665–1668. 5 Montoya JG, Chaparro SV, Celis D, et al. Invasive aspergillosis in the setting of cardiac transplantation. Clin Infect Dis 2003; 37: 281–292. 6 Rijnders BJ, Cornelissen JJ,...
متن کاملItraconazole, an effective adjunctive treatment for allergic bronchopulmonary aspergillosis.
We report the case of a 21-year old man with a long-standing history of severe asthma and allergic rhinosinusitis who developed progressive worsening of dyspnea, wheezing, productive cough, and nasal obstruction, with little response to antibiotics and repeated short courses of oral corticosteroids. A diagnosis of allergic bronchopulmonary aspergillosis was made on the basis of a combination of...
متن کاملAllergic bronchopulmonary aspergillosis--a clinical review.
Allergic Bronchopulmonary Aspergillosis (ABPA) was first described by Hinson and colleagues in 1952. ABPA is a hypersensitivity disorder induced by a fungus Aspergillus and affects non-immunocompromised patients. The diagnosis is based on the presence of a combination of clinical, biological and radiological criteria. The treatment is based on oral corticosteroids for 6-8 weeks at acute phase o...
متن کامل